Nidus Prime · Acquisition
How to get every piece
Base Nidus on Oestrus (Infested Salvage, Rot C). Prime is vaulted — Resurgence or trade. Persistence from Roathe. Augments from Steel Meridian or Perrin.
If you just want Nidus
Nidus
Nidus Prime is vaulted (since 27 July 2023). Unvaults through Prime Resurgence. Base Nidus is always farmable from Infested Salvage.
Fastest route: Base Nidus — Infested Salvage. The Glast Gambit → Play the mode → Stay for Rot C
Need: Eris Salvage · Prime vaulted
Everything else — mods, arcanes, shards — is below. Don’t farm those to craft the Warframe.
Warframe Market
Nidus Prime set
Live sell orders. Whisper a seller in trade chat, meet in a Dojo or Maroo’s Bazaar. Platinum moves in the trade window.
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Where to go
Infested Salvage · Eris / Oestrus
Gold ring is the body to open when this farm lives on the Star Chart. Dojo, Nightwave, and 1999 farms are called out in the walk below.
Infested dwarf planet. Oestrus is Infested Salvage — base Nidus parts.
From the Orbiter
Earth → Mars → Ceres → Jupiter → Saturn → Uranus → Neptune → Pluto → Eris
- 1Unlock Eris via the Pluto Junction. The Glast Gambit awards the main Nidus blueprint.
- 2Oestrus is Infested Salvage, not Survival. Keep the infusion between 50 and 100 on both consoles.
- 3Rotation C drops Neuroptics, Chassis, and Systems. Prime is vaulted — Resurgence or trade.
Build requirements
Everything the five loadouts name
One list for the frame. Tick “I own this” on the item page. Farm the rest.
Abundant Mutationaugment
Amber · Casting Speedshard
Arcane Bellicosearcane
Arcane Gracearcane
Arcane Persistencearcane
Archon Continuitymod
Blind Ragemod
Continuitymod
Corrosive Projectionmod
Crimson · Strengthshard
Cunning Driftmod
Emerald · Toxin status damageshard
Growing Powermod
Hunter Adrenalinemod
Insatiableaugment
Intensifymod
Larva Burstaugment
Molt Augmentedarcane
Molt Reconstructarcane
Overextendedmod
Parasitic Vitalityaugment
Power Driftmod
Preparationmod
Primed Continuitymod
Primed Sure Footedmod
Ragemod
Roar (Rhino)helminth
Steel Fibermod
Streamlinemod
Stretchmod
Tauforged Azure · Armorshard
Teeming Virulenceaugment
Transient Fortitudemod
Umbral Fibermod
Umbral Intensifymod
Violet · Primary crit / electricshard
Vitalitymod
Nidus Prime
Nidus Prime is vaulted (since 27 July 2023). Unvaults through Prime Resurgence. Base Nidus is always farmable from Infested Salvage.
- 1The Glast GambitBase Nidus quest. Oestrus on Eris unlocks after.
- 2Infested Salvage — Oestrus, ErisRotation C drops Neuroptics, Chassis, Systems, and the main blueprint. Unique mode: keep the Infested infusion between 50–100 on two consoles.
- 3Prime is vaultedRelics are vaulted. When Resurgence is up, crack Axi / Lith / Meso / Neo N-series relics. Otherwise buy a set or wait.
Relics are vaulted. When Resurgence is up, crack Axi / Lith / Meso / Neo N-series relics. Otherwise buy a set or wait.
| Part | Relics |
|---|---|
| Blueprint | Axi A14, Lith K10 / R2 / S17 / T9, Meso N12 / P8 / R5 (uncommon, vaulted) |
| Chassis | Axi N12, Lith N12 / N7, Meso N13 / N14, Neo N18 (rare, vaulted) |
| Neuroptics | Axi N10 / N9, Neo N16, Neo S19 (rare / uncommon, vaulted) |
| Systems | Meso A3 / B5 / D7 / H2 / P9, Neo A8 / C2 / N19 (common, vaulted) |
Farm routes
Neuroptics · Chassis · Systems · Blueprint
Base Nidus — Infested Salvage
Fastest ~1 hour · typical ~2 hours · RNG — trade if it bricks your evening
If you only want Prime, skip this — but you still need the base to craft Prime.
Vaulted set · Prime Resurgence
Nidus Prime relics
Fastest ~30–45 min · typical ~1 hour · Variable if the drop is stingy
Prime is the armor and energy bump that makes Persistence comfortable. Base Nidus can still run every build.
Teeming · Larva Burst · Parasitic Vitality · Insatiable · Abundant Mutation
Nidus augments
Fastest ~30–45 min · typical ~1 hour · Variable if the drop is stingy
Priority: Parasitic Vitality, then Teeming Virulence. The rest are build-specific.
Roathe · 5 Maphica · rank 5 needs 21 copies
Arcane Persistence
Fastest ~30–45 min · typical ~1 hour · Variable if the drop is stingy
This arcane also randomly shows on Steel Path Descendia weeks. Buying is faster.
Intensify · Fiber · Vitality
Umbral mods
Fastest ~1 hour · typical ~2 hours · Variable if the drop is stingy
How to get the named cards
Watch
Farm videos
Where To Farm Nidus
Glast Gambit for the main blueprint, then Oestrus Infested Salvage Rotation C for the three parts. The farm never moved. Prime is a vaulted relic set — this is the always-on path.